April 4, 2026

Asset Control and Quality

Investment for the Future

2 Top Stocks to Buy and Hold for the Long Term

2 Top Stocks to Buy and Hold for the Long Term
  • Novartis has proved that it can navigate headwinds such as patent cliffs and a slow economy.

  • Shopify’s long-term ambitions are off to a great start, given its large addressable market and economic moat.

  • 10 stocks we like better than Novartis ›

Long-term investing is easy and relatively stress-free, at least in principle. All you have to do is purchase shares of quality companies and sit back and watch for years — sometimes decades — as the value of your investment rises. However, there are several factors that make this strategy somewhat more complicated than it appears.

One of them is the challenge of picking which stocks to invest in. Making the wrong choice will not lead to a stress-free ride — quite the opposite. In that spirit, let’s consider two companies that are solid long-term investment candidates: Novartis (NYSE: NVS) and Shopify (NASDAQ: SHOP).

Physician talking to patient.
Image source: Getty Images.

While medical drugs will always be in high demand, not every pharmaceutical company is a worthwhile long-term investment. Novartis, though, is. Let’s consider several reasons.

First, it has proved to be highly innovative and boasts a deep and diversified pipeline of products across several therapeutic areas. As of Sept. 30, 10 of Novartis’ products had already generated over $1 billion in sales each, and several more are on the way to cross that mark by the end of the year. Most of these products also saw at least decent revenue growth.

Second, Novartis can address one of the biggest threats pharmaceutical companies face: patent cliffs. It recently lost patent exclusivity for Entresto, a medication to treat chronic heart failure. Yet even with generics entering the market, the company’s revenue and earnings growth remain decent. In the third quarter, the top line increased by 8% year over year to $13.9 billion, while earnings per share came in at $2.25, 9% higher than the year-ago period.

These are solid — though not excellent or exceptional — numbers for a pharmaceutical giant. But in the context of a patent cliff for a best-selling drug, they’re much more impressive.

How did Novartis pull it off? The company’s diversified lineup helped. That includes relatively new launches, like Fabhalta, a medicine for paroxysmal nocturnal hemoglobinuria (a rare blood disease) that first earned approval in the U.S. in December 2023. Novartis’ ability to replenish its lineup and earn label expansions for existing products should allow it to navigate patent cliffs in the future as well.

Third, Novartis is a fantastic dividend company. It has increased its payouts for 28 consecutive years and currently offers a forward yield of 3%, higher than the S&P 500‘s average of 1.2%.

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